Research progress on the negative factors of corneal endothelial cells proliferation

The human corneal endothelium forms a boundary layer between anterior chamber and corneal stoma. The corneal endothelial cells are responsible for maintaining cornea transparency, which is very vital for our visual acuity, via its pump and barrier functions. The adult corneal endothelial cells in vivo lack proliferation in response to the cell loss caused by outer damages and diseases. As a result, in order to compensate for cell loss, corneal endothelial cells migrate and enlarge while not via dividing to increase the endothelial cell density. Therefore, it is not capable for corneal endothelium to restore the corneal clarity. Some researches have proved that in vitro the corneal endothelial maintained proliferation ability. This review describes the current research progress regarding the negative factors that inhibit proliferation of the corneal endothelial cells. This review will mainly present several genes and proteins that inhibit the proliferation of the corneal endothelial cells, of course including some other factors like enzymes and position.     

Accuracy of 3D reproduction of natural head position using three different manual reorientation methods compared to 3D software

Purpose

The aim of this study was to analyze the positional differences of three-dimensional (3D) natural head positions (NHPs) reproduced by three different manual reorientation methods without special software by the Pose from Orthography and Scaling with ITerations (POSIT) method.

Relationships of vertical facial pattern,natural head position and craniocervical posture in young Chinese children

Objective: To investigate relationships of vertical facial patterns, natural head position (NHP), and craniocervical posture in young Chinese children with skeletal Class I relationship.

Methods: Ninety-four patients with skeletal Class I relationship were classified into low, average, and high angle groups according to their mandibular plane angle (NSL/ML). Cephalometric radiographs in NHP were taken. Variables representing vertical and sagittal craniofacial morphology, head posture, and craniocervical posture were measured and compared.

Results: Inclinations of the mandible to the true vertical and cervical column were smallest in the high angle group and largest in the low angle group. Other variables representing head posture and craniocervical posture were largest in the high angle group, smallest in the low angle group. Inclinations of ramus to cervical column were largest in the high angle group and smallest in the low angle group.

Discussion: Subjects with large NSL/ML angles showed extended head and craniocervical posture, while subjects with small NSL/ML angles exhibited flexed head and craniocervical posture.     

Dynamic Irrigation Promotes Apical Papilla Cell Attachment in an Ex Vivo Immature Root Canal Model

Introduction

The use of dentin preconditioning techniques in regenerative endodontic procedures is currently promising. Several growth factors have been detected on dentin after ultrasonic irrigation with EDTA. This study aimed to evaluate the effects of dynamic irrigation with different solution regimens on apical papilla cell (APC) attachment in an ex vivo immature tooth model.

The advantages of advanced computer-assisted diagnostics and three-dimensional preoperative planning on implant position in orbital reconstruction

Objective

Advanced three-dimensional (3D) diagnostics and preoperative planning are the first steps in computer-assisted surgery (CAS). They are an integral part of the workflow, and allow the surgeon to adequately assess the fracture and to perform virtual surgery to find the optimal implant position. The goal of this study was to evaluate the accuracy and predictability of 3D diagnostics and preoperative virtual planning without intraoperative navigation in orbital reconstruction.

New Acceptor–Donor–Acceptor Systems Based on Bis-(Imino-1,8-Naphthalimide)

In this paper, six novel symmetrical bis-(imino-1,8-naphthalimides) differing in core and N-substituent structure were synthesized, and their thermal (TGA, DSC), optical (UV-Vis, PL), electrochemical (DPV, CV) properties were evaluated. The compounds were stable to 280 °C and could be transferred into amorphous materials. Electrochemical investigations showed their ability to occur reductions and oxidations processes. They exhibited deep LUMO levels of about −3.22 eV and HOMO levels above −5.80 eV. The optical investigations were carried out in the solutions (polar and non-polar) and in films and blends with PVK:PBD. Bis-(imino-1,8-naphthalimides) absorbed electromagnetic radiation in the range of 243–415 nm and emitted light from blue to yellow. Their capacity for light emission under voltage was preliminarily tested in devices with an active layer consisting of a neat compound and a blend with PVK:PBD. The diodes emitted green or red light.     

Effects of the Ultrasonic Assisted Surface Rolling Process on the Fatigue Crack Initiation Position Distribution and Fatigue Life of 51CrV4 Spring Steel

In this paper, the effects of the fatigue crack initiation position (FCIP) on fatigue life are discussed. Different modified gradient fields (MGFs) are prepared on the surface of 51CrV4 spring steel components by an ultrasonic assisted surface rolling process (USRP). Subsequently, the fatigue behaviour of steels with different FCIPs is systematically studied. The results show that the fatigue life of steels first exhibits an increasing tendency and then a decreasing tendency with increasing distance between an FCIP and the surface. When an FCIP shifts from the surface of the sample to the interior, the fatigue crack initiation resistance on the interior is greater than that on the surface, which leads to an increase in fatigue life. However, when the FCIP further shifts towards the centre of the specimen, the stress triaxiality experienced by the fatigue source gradually increases, which results in a peak in the curve of FCIP versus fatigue life. The magnitude of this peak fatigue life is related to the change in the stress triaxiality. Moreover, according to focused ion beam-high-resolution transmission electron microscopy (FIB-HRTEM) microstructural analysis near FCIPs, under a higher stress triaxiality, the crack tip area is subject to greater stress constraints, making the multiplication and movement of dislocations in this area more difficult, resulting in the decrease in movable dislocation density. This decrease in dislocation density leads to an increase in the stress concentration and accelerates the crack growth rate, decreasing the fatigue life. Therefore, the significant change in fatigue life is controlled by the MGF and stress triaxiality.